It is a little bug of Springer's website, we are contacting Springer for fixing this bug. xla, then everything will go smoothly as directed in Installation Structions Document. xls downloaded from the Springer's website into 12248_2010_9185_MOESM2_ESM. To install DDSolver on your computer, you should first change the 12248_2010_9185_MOESM2_ESM. In addition, a detailed disscusion of the approaches for estimating similarity between dissolution profiles was supplied as Supplementary File. The DDSolver software is available at the Electronic Supplementary Materials page of the paper's website. You can download it from the Spriger's website providing you have the right to access the fulltext of the Springer Database.ĭDSolver is a freely available program which is capable of performing most existing techniques for comparing drug release data, including exploratory data analysis, univariate ANOVA, ratio test procedures, the difference factor f 1, the similarity factor f 2, the Rescigno indices, the 90% confidence interval (CI) of difference method, the multivariate statistical distance method, the model-dependent method, the bootstrap f 2 method, and Chow and Ki’s time series method. ![]() Most recently, we have developed a powerful software, named DDSolver, for estimating drug dissolution/release similarity.
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